Title :
Graph Mining of Networks from Genome Biology
Author :
Chin, George, Jr. ; Nakamura, Grant C. ; Chavarria, Daniel G. ; Sofia, Heidi J.
Author_Institution :
Pacific Northwest Nat. Lab., Richland
Abstract :
We are developing an advanced toolkit for biological networks, using problems from genome biology to drive this work. We now share our experiences in graph analysis and visualization of microbial genome networks using a collection of new and existing graph mining tools and techniques. We address three key problems in genome biology: the organization of complete genome protein networks, feature extraction across chromosomes in microbial strains, and hierarchical structure of protein families and superfamilies.
Keywords :
biology computing; data mining; genetics; molecular biophysics; proteins; chromosomes; feature extraction; graph mining; hierarchical structure; microbial genome networks; protein; Bioinformatics; Biological cells; Biology computing; Capacitive sensors; Computational biology; Genomics; Laboratories; Large-scale systems; Open source software; Proteins;
Conference_Titel :
Bioinformatics and Bioengineering, 2007. BIBE 2007. Proceedings of the 7th IEEE International Conference on
Conference_Location :
Boston, MA
Print_ISBN :
978-1-4244-1509-0
DOI :
10.1109/BIBE.2007.4375728
