Title :
The CAI instrument: A novel optical device for sepsis analysis for POCT applications
Author :
Baldini, F. ; Giannetti, A. ; Trono, C. ; Bolzoni, L. ; Porro, G.
Author_Institution :
IFAC-CNR, Sesto Fiorentino, Italy
fDate :
Aug. 28 2011-Sept. 1 2011
Abstract :
In the last years, there has been a strong request of the physicians for point-of-care testing (POCT) instrumention. The present paper deals with the characterisation of a POCT optical instrument, the channel array interrogation (CAI) device, developed for the simultaneous detection of biomarkers for sepsis. The portable device was optimized for the determination of procalcitonin (PCT) and C-reactive protein (CRP), the main biomarkers for sepsis. Limit of detection equal to 1.3 μg L-1 and to 2 μg L-1 for CRP and PCT, respectively were achieved.
Keywords :
biomedical optical imaging; diseases; patient treatment; proteins; C-reactive protein; biomarkers; channel array interrogation instrument; optical device; optical instrument; physicians; point-of-care testing; sepsis analysis; Biomarkers; Biomedical optical imaging; Fluorescence; Geometrical optics; Instruments; Optical sensors;
Conference_Titel :
Quantum Electronics Conference & Lasers and Electro-Optics (CLEO/IQEC/PACIFIC RIM), 2011
Conference_Location :
Sydney, NSW
Print_ISBN :
978-1-4577-1939-4
DOI :
10.1109/IQEC-CLEO.2011.6194077
