• DocumentCode
    1992992
  • Title

    A Modified Uniformization Method for the Chemical Master Equation

  • Author

    Zhang, Jingwei ; Watson, Layne T.

  • Author_Institution
    Virginia Polytech. Inst. & State Univ., Blacksburg
  • fYear
    2007
  • fDate
    14-17 Oct. 2007
  • Firstpage
    1429
  • Lastpage
    1433
  • Abstract
    The chemical master equation is considered an accurate description of general chemical systems, and especially so for modeling cell cycle and gene regulatory networks. This paper proposes an efficient way of solving the chemical master equation for some prototypical problems in systems biology. A comparison between this new approach and some traditional approaches is also given.
  • Keywords
    biochemistry; cellular biophysics; genetics; master equation; cell cycle; chemical master equation; gene regulatory networks; general chemical systems; systems biology; Biological system modeling; Chemical analysis; Computational modeling; Computer science; Differential equations; Mathematical model; Mathematics; Partial differential equations; Random variables; Stochastic processes;
  • fLanguage
    English
  • Publisher
    ieee
  • Conference_Titel
    Bioinformatics and Bioengineering, 2007. BIBE 2007. Proceedings of the 7th IEEE International Conference on
  • Conference_Location
    Boston, MA
  • Print_ISBN
    978-1-4244-1509-0
  • Type

    conf

  • DOI
    10.1109/BIBE.2007.4375761
  • Filename
    4375761