Title :
The effect of interburst intervals on measures of hippocampal LTP in the freely moving adult male rat
Author :
Fortin, D.A. ; Bai, J. ; Campos, M. ; Bronzino, J.D.
Author_Institution :
Dept. of Eng., Trinity Coll., Hartford, CT, USA
Abstract :
An important factor in the induction and maintenance of long term potentiation (LTP) is the tetanization paradigm. This paper presents the changes associated with the induction and maintenance of hippocampal LTP in the freely moving adult male rat, subjected to three different tetanization paradigms. These results indicate that specific LTP measures are dependent on the bursting paradigm in chronic recording studies in freely moving animals
Keywords :
bioelectric potentials; brain; neurophysiology; brain function; bursting paradigm; chronic recording studies; evoked potentials; freely moving adult male rat; hippocampal long term potentiation; interburst intervals effect; mediant perforant pathway; neuron firing; potentiation induction; potentiation maintenance; synaptic potentiation; tetanization paradigm; Animals; Biological information theory; Educational institutions; Electrodes; Frequency; Information processing; Pulse measurements; Rats; Space vector pulse width modulation; Testing;
Conference_Titel :
Bioengineering Conference, 2000. Proceedings of the IEEE 26th Annual Northeast
Conference_Location :
Storrs, CT
Print_ISBN :
0-7803-6341-8
DOI :
10.1109/NEBC.2000.842401
