Development of pen-shaped portable biochemical reaction system based on magnetic beads handling

We newly introduced a pen-shaped platform like a mechanical pencil, in which an inchworm motion is used to transport the cylinder-shaped reaction unit, to produce a portable biochemical reaction system. The specifications were decided for an application to blood analysis, and the reaction unit was fabricated. The outer diameter and length of the unit were 7.0 and 80.0 mm. The mechanical pencil device produced by Mitsubishi Pencil Co., Ltd was used as the pen-shaped platform for driving the reaction unit. The system successfully manipulated the magnetic beads in a droplet in the reaction unit.