A review on the requirements of modelling of blood flow

The critical issue to model blood flow in mesoscale or microscale is impossible to consider all blood constituents. First, we clarify blood flow which consisting of different constituents. Platelets are the most influential constituent to affect thrombosis process after comparison of all blood constituents. Consequently, critical issue can be solved by selecting platelets as the only constituent to model in mesoscale or microscale. Some numerical techniques to solve blood flow modelling in biomechanics are reviewed. In conclusion, the review shows that multiscale modelling of blood flow is required because combining the advantages of macroscale-mesoscale enable sufficient computational efficiency with high accuracy. Therefore, multiscale modelling of platelets is highly recommended.