Title :
Infrared evanescent wave bio-sensors
Author :
Lucas, Jacques ; Bureau, Bruno ; Pledel, Catherine Boussard ; Kierse, Julie ; Anne, Marie-Laure ; Lucas, Pierre ; Riley, Mark
Author_Institution :
Glass & Ceramic Lab., Rennes Univ., France
Abstract :
Original tapered infrared chalcogenide glass fibers have been developed in order to analyse by evanescent wave absorption the IR signatures of biomolecules in the 2 to 12 μm range. In using a small contact between the fiber and the analytes, in situ measurements have been performed on biofilms, serum, liver and lung cells allowing the detection of metabolic anomalies.
Keywords :
biosensors; cellular biophysics; fibre optic sensors; infrared spectra; liver; microorganisms; molecular biophysics; tumours; analytes; biofilms; biomolecules; evanescent wave absorption; infrared evanescent wave biosensors; liver; lung cells; metabolic anomalies; serum; tapered infrared chalcogenide glass fibers; Cells (biology); Electromagnetic wave absorption; Glass; Infrared detectors; Infrared spectra; Liver; Lungs; Molecular biophysics; Optical fibers; Optical surface waves;
Conference_Titel :
Lasers and Electro-Optics Society, 2004. LEOS 2004. The 17th Annual Meeting of the IEEE
Print_ISBN :
0-7803-8557-8
DOI :
10.1109/LEOS.2004.1363494
