Title :
Endoscopic PDT applications of intense femtosecond laser pulses through hollow-fibers and graded-index multimode fibers
Author :
Kamino, L. ; Hagiwara, Y. ; Shimada, T. ; Obara, M. ; Hongo, A.
Author_Institution :
Dept. of Electron. & Electr. Eng., Keio Univ., Yokohama, Japan
Abstract :
The paper reports on the study of intense femtosecond laser delivery through small-core, 320-μm hollow fibers and through large core graded-index optical fibers. The work also demonstrates the feasibility of endoscopic cancer treatment with PDT excited by fiber delivered, intense Ti:sapphire femtosecond laser pulses. The Ti:sapphire laser excitation of photofrin and indocyanine green (ICG) is studied in vitro experiment.
Keywords :
cancer; endoscopes; gradient index optics; high-speed optical techniques; laser applications in medicine; optical fibres; photodynamic therapy; 320 mum; Al2O3:Ti; Ti:sapphire femtosecond laser pulses; core graded-index optical fibers; endoscopic PDT; endoscopic cancer treatment; graded-index multimode fibers; hollow-fibers; indocyanine green; photofrin; Fiber lasers; Laser beams; Laser excitation; Laser modes; Optical fiber cables; Optical fiber dispersion; Optical fibers; Optical pulses; Ultrafast electronics; Ultrafast optics;
Conference_Titel :
Lasers and Electro-Optics Society, 2004. LEOS 2004. The 17th Annual Meeting of the IEEE
Print_ISBN :
0-7803-8557-8
DOI :
10.1109/LEOS.2004.1363499