Comparative methods of spike detection in epilepsy

Epilepsy is a common neurological condition which affects the central nervous system that causes people to have a seizure and can be assessed by electroencephalogram (EEG). Electroencephalography (EEG) signals reflect two types of paroxysmal activity: ictal activity and interictal paroxystic events (IPE). The relationship between IPE and ictal activity is an essential and recurrent question in epileptology. The spike detection in EEG is a difficult problem. Many methods have been developed to detect the IPE in the literature. In this paper we propose three methods to detect the spike in real EEG signal: Page Hinkley test, smoothed nonlinear energy operator (SNEO) and fractal dimension. Before using these methods, we filter the signal. The Singular Spectrum Analysis (SSA) filter is used to remove the noise in an EEG signal.