A Molecular Dynamics Study of Thermal Ablation

Author

Lin, David T. W. ; Hu, Yuh-Chung

Author_Institution

Mech. Eng., Far East Coll., Hsin-Shih

fYear

2006

fDate

18-21 Jan. 2006

Firstpage

594

Lastpage

598

Abstract

The bio-heat transfer problem and the thermal ablation in bio-tissue require general solutions for the control of the external heating power. An algorithm based on the molecular dynamics (MD) and the GROMACS protein data bank is developed to solve the bio-heat transfer problem. The value of the thermal conductivity of alanine is calculated from the autocorrelation function of the Green-Kubo formalism and resulted in the knowledge of the power control. Moreover, this paper constructs a bio-tissue heat transfer model and it expands the application of thermal science to the bio-medical field.

Keywords

biological tissues; biothermics; heat transfer; molecular biophysics; molecular dynamics method; proteins; thermal conductivity; GROMACS protein data bank; Green-Kubo formalism; alanine; autocorrelation function; bioheat transfer; biotissue; molecular dynamics study; thermal ablation; thermal conductivity; Amino acids; Biological materials; Heat transfer; Medical treatment; Power system modeling; Protein engineering; Systems engineering and theory; Temperature control; Thermal conductivity; Thermal engineering; Alanine; MD; bio-heat; thermal ablation;

fLanguage

English

Publisher

ieee

Conference_Titel

Nano/Micro Engineered and Molecular Systems, 2006. NEMS '06. 1st IEEE International Conference on

Conference_Location

Zhuhai

Print_ISBN

1-4244-0139-9

Electronic_ISBN

1-4244-0140-2

Type

conf

DOI

10.1109/NEMS.2006.334852

Filename

4135025