A Portable System for Determination of Biochemical Parameters by Optic Reflection

Author

Zhou, Aiyu ; He, Baoshan ; Wang, Hui ; Jiang, Liying ; Cai, Xinxia

Author_Institution

State Key Lab. of Transducer Technol., Chinese Acad. of Sci., Beijing

fYear

2006

fDate

18-21 Jan. 2006

Firstpage

1105

Lastpage

1108

Abstract

A portable system for determination of biochemical parameters by optic reflection is described in this paper. This system worked in visible spectral range of 400~700 nm and the spectrum resolution was 10 nm. The detected parameter´s concentration is calculated mathematically according to the calibration equation established between the index of reflection and the reference concentration. Combined with the biosensors developed by our group, the system was used to determine Hemoglobin (HB) and Alanine Aminotransferase (ALT), which were two preferred biochemical parameters for the evaluation in blood dedication. The detection of HB and ALT were experimentalized in National Center for Clinical Laboratories (NCCL) of China and Red Cross Blood Center of Beijing, China respectively. And the detected results correlated well with that obtained by the large equipments employed by the two centers mentioned above. Compared to large equipments used in traditional method, this system is portable, rapid to get results and can be operated simply

Keywords

biomedical engineering; biomedical optical imaging; biosensors; blood; enzymes; light reflection; Alanine Aminotransferase detection; Beijing; China; Hemoglobin detection; NCCL; National Center for Clinical Laboratories; Red Cross Blood Center; biosensors; blood dedication; calibration equation; optic reflection; portable biochemical parameter determination system; reflection index; spectrum resolution; visible spectral range; Amino acids; Biomedical optical imaging; Blood; Calibration; Equations; Laboratories; Optical design; Optical detectors; Optical reflection; Systems engineering and theory; Alanine Aminotransferas; Hemoglobin; biochemical parameters detection; optic reflection; portable system; spectrophotometer;

fLanguage

English

Publisher

ieee

Conference_Titel

Nano/Micro Engineered and Molecular Systems, 2006. NEMS '06. 1st IEEE International Conference on

Conference_Location

Zhuhai

Print_ISBN

1-4244-0139-9

Electronic_ISBN

1-4244-0140-2

Type

conf

DOI

10.1109/NEMS.2006.334641

Filename

4135140