Title :
A New Type of Bio-Chemical Sensor Based on SPM
Author :
Zhao, Huibin ; Ren, Quan ; Lin, Yunsheng ; Zuo, Yansheng ; Han, Li
Author_Institution :
Inst. of Electr. Eng., Chinese Acad. of Sci., Beijing
Abstract :
A new type of bio-chemical sensor based on SPM was designed and fabricated in this paper. The bio-chemical sensor uses the SPM head as the probe part, which can convert the physical variation quantity on the micro-cantilever to electrical signals, and finally change it into image. In the experiment, the bio-chemical sensor based on SPM is used to detect two kinds of ssDNA molecules in PBS solution. By comparing the data in our experiment with that in other experiment, it can be seen that detecting unknown DNA molecules and other chemical or biological molecules in solution by this type of bio-chemical sensor is efficient and practical
Keywords :
DNA; biosensors; chemical sensors; scanning probe microscopy; SPM based biochemical sensor; SPM head probe; electrical signals; microcantilever; phosphate buffer solution; scanning probe microscopy; sensor design; sensor fabrication; ssDNA molecule detection; Acoustic sensors; Biosensors; Chemical and biological sensors; Design engineering; Optical sensors; Optical surface waves; Resonance; Resonant frequency; Scanning probe microscopy; Surface acoustic waves; SPM; bio-chemical sensor; micro-cantilever;
Conference_Titel :
Nano/Micro Engineered and Molecular Systems, 2006. NEMS '06. 1st IEEE International Conference on
Conference_Location :
Zhuhai
Print_ISBN :
1-4244-0139-9
Electronic_ISBN :
1-4244-0140-2
DOI :
10.1109/NEMS.2006.334672
