Title :
Development of Transient Absorption Ultrasonic Microscopy
Author :
Applegate, Brian E. ; Shelton, Ryan L.
Author_Institution :
Dept. of Biomed. Eng., Texas A&M Univ., College Station, TX, USA
Abstract :
The authors have developed a novel, hybrid imaging modality, Transient Absorption Ultrasonic Microscopy (TAUM), which takes advantage of the optical nonlinearities afforded by transient absorption to achieve ultrahigh-resolution photoacoustic microscopy. The theoretical point spread function for TAUM is functionally equivalent to confocal and two-photon fluorescence microscopy, potentially enabling cellular/subcellular photoacoustic imaging.
Keywords :
acoustic microscopy; fluorescence; nonlinear optics; optical transfer function; photoacoustic effect; cellular/subcellular photoacoustic imaging; confocal fluorescence microscopy; hybrid imaging modality; optical nonlinearities; point spread function; transient absorption ultrasonic microscopy; two-photon fluorescence microscopy; ultrahigh-resolution photoacoustic microscopy; Biomedical optical imaging; Microscopy; Optical diffraction; Optical microscopy; Optical pulses; Spatial resolution;
Conference_Titel :
Lasers and Electro-Optics Europe (CLEO EUROPE/EQEC), 2011 Conference on and 12th European Quantum Electronics Conference
Conference_Location :
Munich
Print_ISBN :
978-1-4577-0533-5
Electronic_ISBN :
Pending
DOI :
10.1109/CLEOE.2011.5943231
