Development of Transient Absorption Ultrasonic Microscopy

Author

Applegate, Brian E. ; Shelton, Ryan L.

Author_Institution

Dept. of Biomed. Eng., Texas A&M Univ., College Station, TX, USA

fYear

2011

fDate

22-26 May 2011

Firstpage

1

Lastpage

1

Abstract

The authors have developed a novel, hybrid imaging modality, Transient Absorption Ultrasonic Microscopy (TAUM), which takes advantage of the optical nonlinearities afforded by transient absorption to achieve ultrahigh-resolution photoacoustic microscopy. The theoretical point spread function for TAUM is functionally equivalent to confocal and two-photon fluorescence microscopy, potentially enabling cellular/subcellular photoacoustic imaging.

Keywords

acoustic microscopy; fluorescence; nonlinear optics; optical transfer function; photoacoustic effect; cellular/subcellular photoacoustic imaging; confocal fluorescence microscopy; hybrid imaging modality; optical nonlinearities; point spread function; transient absorption ultrasonic microscopy; two-photon fluorescence microscopy; ultrahigh-resolution photoacoustic microscopy; Biomedical optical imaging; Microscopy; Optical diffraction; Optical microscopy; Optical pulses; Spatial resolution;

fLanguage

English

Publisher

ieee

Conference_Titel

Lasers and Electro-Optics Europe (CLEO EUROPE/EQEC), 2011 Conference on and 12th European Quantum Electronics Conference

Conference_Location

Munich

ISSN

Pending

Print_ISBN

978-1-4577-0533-5

Electronic_ISBN

Pending

Type

conf

DOI

10.1109/CLEOE.2011.5943231

Filename

5943231