DocumentCode :
2078119
Title :
Methods for estimation of demographic parameters from DNA sequence samples
Author :
Polanski, Andrzej ; Kimmel, Marek
Author_Institution :
Dept. of Stat., Rice Univ., Houston, TX, USA
Volume :
5
fYear :
2002
fDate :
2002
Firstpage :
3472
Abstract :
The paper shows basic mathematical methodology of modeling genetic neutral evolution, including Fisher-Wright process statistics, appropriate models of mutation and coalescence method, and overviews recent results in the area. The basic approach is the use of maximum likelihood techniques. However due to computational problems, other more intuitive or approximate methods are also of great importance.
Keywords :
DNA; computational complexity; demography; evolution (biological); maximum likelihood estimation; DNA sequence samples; Fisher-Wright process statistics; coalescence method; computational problems; demographic parameter estimation; genetic neutral evolution; maximum likelihood techniques; mutation; Automation; Biological system modeling; DNA; Demography; Evolution (biology); Genetic mutations; Mathematical model; Parameter estimation; Sequences; Statistics;
fLanguage :
English
Publisher :
ieee
Conference_Titel :
American Control Conference, 2002. Proceedings of the 2002
ISSN :
0743-1619
Print_ISBN :
0-7803-7298-0
Type :
conf
DOI :
10.1109/ACC.2002.1024464
Filename :
1024464
Link To Document :
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