DocumentCode
2080724
Title
Simulation of a nobel porous Si based cantilever beam CA 15-3 protein sensor
Author
Gharaei, H. ; Nikfarjam, A. ; Mohamadnejad, J. ; Saniei, F.
fYear
2013
fDate
13-15 Feb. 2013
Firstpage
178
Lastpage
182
Abstract
In this paper a cantilever beam Bio-sensor based on porous Si has been simulated. Adding the mass of a CA 15-3 protein to the mass of the cantilever beam can make a frequency shift, which is used for the measurement. Here a sensitivity of S = 4.896×107 Hz/μg for detection CA 15-3 protein with mass of m = 4.982×10-10 ng has been achieved. Having the surface of the sensor porous let us make sensors with such sensitivities. Porous cantilever beam caused the sensitivity and the bandwidth of the biosensor increase, and saturation takes place at higher number of CA 15-3 proteins absorbed. Besides porous sensor showed lower threshold.
Keywords
biomedical transducers; biosensors; cantilevers; elemental semiconductors; mass measurement; proteins; silicon; tumours; Si; human tumor mucin; mass measurement; porous Si based cantilever beam CA 15-3 protein biosensor; sensor porous surface; Finite element analysis; Gold; Silicon; Bio Sensor; Cantilever Beam; Porous Si;
fLanguage
English
Publisher
ieee
Conference_Titel
Robotics and Mechatronics (ICRoM), 2013 First RSI/ISM International Conference on
Conference_Location
Tehran
Print_ISBN
978-1-4673-5809-5
Type
conf
DOI
10.1109/ICRoM.2013.6510101
Filename
6510101
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