Title :
A Bionic Neural Link for peripheral nerve repair
Author :
Yong Ping Xu ; Shih-Cheng Yen ; Ng, Kian Ann ; Xu Liu ; Ter Chyan Tan
Author_Institution :
Dept. of Electr. & Comput. Eng., Nat. Univ. of Singapore, Singapore, Singapore
fDate :
Aug. 28 2012-Sept. 1 2012
Abstract :
Peripheral nerve injuries with large gaps and long nerve regrowth paths are difficult to repair using existing surgical techniques, due to nerve degeneration and muscle atrophy. This paper proposes a Bionic Neural Link (BNL) as an alternative way for peripheral nerve repair. The concept of the BNL is described, along with the hypothetical benefits. A prototype monolithic single channel BNL has been developed, which consists of 16 neural recording channels and one stimulation channel, and is implemented in a 0.35-μm CMOS technology. The BNL has been tested in in-vivo animal experiments. Full function of the BNL chip has been demonstrated.
Keywords :
CMOS integrated circuits; biomedical equipment; cellular biophysics; injuries; muscle; neurophysiology; surgery; BNL chip; CMOS technology; bionic neural link; hypothetical benefits; in-vivo animal experiments; long nerve regrowth paths; muscle atrophy; nerve degeneration; neural recording channels; peripheral nerve injuries; peripheral nerve repairing; prototype monolithic single channel BNL; stimulation channel; surgical techniques; Current measurement; Electrodes; Frequency measurement; Multiplexing; Semiconductor device measurement; Surgery; Wrist; Animals; Bionics; Electric Stimulation; Neural Prostheses; Neurosurgical Procedures; Peripheral Nerve Injuries; Rats; Rats, Wistar; Sciatic Nerve; Signal Processing, Computer-Assisted;
Conference_Titel :
Engineering in Medicine and Biology Society (EMBC), 2012 Annual International Conference of the IEEE
Conference_Location :
San Diego, CA
Print_ISBN :
978-1-4244-4119-8
Electronic_ISBN :
1557-170X
DOI :
10.1109/EMBC.2012.6346184
