Anisotropic Asymmetry Analysis in Diffusion Tensor Images of Healthy an Heroin-dependent Subjects

We apply a promising voxel-based method to the left/right anisotropic asymmetric analysis of fractional anisotropy (FA) in diffusion tensor images. Firstly, we calculated the FA values for each subject voxel-by-voxel. Secondly, we expanded the method of optional voxel-based morphometry (OVBM) to create a better template to normalize FA images in the preprocessing step. Finally the asymmetric analyzing approach we developed earlier was used to directly detect the different asymmetries between healthy and heroin-dependent subjects. Results showed the abnormal asymmetries in heroin-dependent subjects.