Title :
Database for Development of the Cultured Neuronal Network
Author :
Li, Xiangning ; Pu, Jiangbo ; Zhu, Geng ; Chen, Wenjuan ; Zhou, Wei ; Luo, Qingming
Author_Institution :
Wuhan Nat. Lab. for Optoelectron., Huazhong Univ. of Sci. & Technol., Wuhan, China
Abstract :
It is generally assumed that the variability of neuronal firing pattern has an important effect on the connectivity of the nervous system, but this effect has not been thoroughly investigated. This challenging research area involves a tight cooperation of neuroscience, computer science, and biomedical engineering among others. In order to share our data and methods with the other experimenters and analysts, we have designed and implemented a database (http://bmp.hust.edu.cn/neuro_db/) including over 6000 GB data recorded from cultured neuronal networks on multi-electrode array. Most of these data were spontaneous activities of 50 cultures during development. The database presented here provides a crucial tool to explore neural development and neural coding, thus enables neuroscientists to share and manage data with greater efficiency.
Keywords :
medical computing; medical information systems; neural nets; neurophysiology; very large databases; biomedical engineering; computer science; cultured neuronal network database; multielectrode array; nervous system; neural coding; neuronal firing pattern; neuroscience; Animals; Biological neural networks; Brain modeling; Data acquisition; Data analysis; Distributed databases; Electrodes; Neurons; Neuroscience; Temperature control;
Conference_Titel :
Biomedical Engineering and Informatics, 2009. BMEI '09. 2nd International Conference on
Conference_Location :
Tianjin
Print_ISBN :
978-1-4244-4132-7
Electronic_ISBN :
978-1-4244-4134-1
DOI :
10.1109/BMEI.2009.5301725