• DocumentCode
    2092780
  • Title

    A Novel Method for Preparation of Ethyl [18F]Fluoroacetate

  • Author

    Sun, Li-Quan ; Mori, Tetsuya ; Furukawa, Takako ; Yonekura, Yoshiharu ; Fujibayashi, Yasuhisa

  • Author_Institution
    Beijing Inst. of Technol., Beijing
  • fYear
    2007
  • fDate
    23-27 May 2007
  • Firstpage
    1883
  • Lastpage
    1886
  • Abstract
    A simple and fast method for preparation of ethyl [18F]fluoroacetate which can be operated by remote control has been established, using distillation for purification. By this development, it has become possible to obtain ethyl [18F]fluoroacetate in a short synthesis time of 29 min and with a reproducible radiochemical yield of 28.6 plusmn 3.6 %, (decay corrected). The radiochemical purity of ethyl [18F]fluoroacetate was more than 95%.
  • Keywords
    distillation; materials preparation; organic compounds; positron emission tomography; purification; radiochemistry; PET tracer; distillation; ethyl [18F]fluoroacetate; purification; radiochemical purity; radiochemical yield; remote control; time 29 min; Biochemistry; Biomedical imaging; Detectors; Nuclear magnetic resonance; Positron emission tomography; Purification; Radio control; Solvents; Sun; Valves;
  • fLanguage
    English
  • Publisher
    ieee
  • Conference_Titel
    Complex Medical Engineering, 2007. CME 2007. IEEE/ICME International Conference on
  • Conference_Location
    Beijing
  • Print_ISBN
    978-1-4244-1077-4
  • Electronic_ISBN
    978-1-4244-1078-1
  • Type

    conf

  • DOI
    10.1109/ICCME.2007.4382075
  • Filename
    4382075