Title :
A Novel Method for Preparation of Ethyl [18F]Fluoroacetate
Author :
Sun, Li-Quan ; Mori, Tetsuya ; Furukawa, Takako ; Yonekura, Yoshiharu ; Fujibayashi, Yasuhisa
Author_Institution :
Beijing Inst. of Technol., Beijing
Abstract :
A simple and fast method for preparation of ethyl [18F]fluoroacetate which can be operated by remote control has been established, using distillation for purification. By this development, it has become possible to obtain ethyl [18F]fluoroacetate in a short synthesis time of 29 min and with a reproducible radiochemical yield of 28.6 plusmn 3.6 %, (decay corrected). The radiochemical purity of ethyl [18F]fluoroacetate was more than 95%.
Keywords :
distillation; materials preparation; organic compounds; positron emission tomography; purification; radiochemistry; PET tracer; distillation; ethyl [18F]fluoroacetate; purification; radiochemical purity; radiochemical yield; remote control; time 29 min; Biochemistry; Biomedical imaging; Detectors; Nuclear magnetic resonance; Positron emission tomography; Purification; Radio control; Solvents; Sun; Valves;
Conference_Titel :
Complex Medical Engineering, 2007. CME 2007. IEEE/ICME International Conference on
Conference_Location :
Beijing
Print_ISBN :
978-1-4244-1077-4
Electronic_ISBN :
978-1-4244-1078-1
DOI :
10.1109/ICCME.2007.4382075
