Title :
Advanced Methods for Target Navigation using Microelectrode Recordings in Stereotactic Neurosurgery for Deep Brain Stimulation
Author :
Gemmar, Peter ; Gronz, Oliver ; Henrichs, Thorsten ; Hertel, Frank
Author_Institution :
Inst. for Innovative Inf. Applic. i3A, Univ. of Appl. Sci. (FH) Trier, Trier
Abstract :
This study describes novel methods for navigating and placing of electrodes into specific structures in the basal ganglia for deep brain stimulation (DBS), as it is common in the treatment of Parkinson´s disease. Critical to these procedures in neurosurgery is the localization and identification of different target structures such as subthalamic nucleus (STN) along the electrode´s trajectory and finding the best position for the stimulating electrode. Typically, microelectrode recordings (MER) of local neural activity along up to five parallel trajectories are used by neurosurgeons for detecting the target region and creating the anatomic positions of the electrodes by imagination. We developed a method for automatic classification of the MER signals, which provides an electrode model with patient specific borders of the STN. In addition, a method is provided for finding the best matching of the electrode model with a 3D model of the STN. As a result, a 2.5D visualization of the target region is produced with the most probable positions of the electrodes and their intersections.
Keywords :
brain; medical signal processing; signal classification; 2.5D visualization; MER signal classification; Parkinson´s disease; basal ganglia; deep brain stimulation; microelectrode recordings; stereotactic neurosurgery; subthalamic nucleus; target navigation; Basal ganglia; Brain stimulation; Electrodes; Microelectrodes; Navigation; Neurosurgery; Parkinson´s disease; Satellite broadcasting; Trajectory; Visualization; DBS; MER classification; STN; deep brain stimulation; microelectrode recordings MER; neurosurgery target navigation; parkinson´s disease;
Conference_Titel :
Computer-Based Medical Systems, 2008. CBMS '08. 21st IEEE International Symposium on
Conference_Location :
Jyvaskyla
Print_ISBN :
978-0-7695-3165-6
DOI :
10.1109/CBMS.2008.54