ACHE: An Architecture for Clinical Hypothesis Examination

Physiological monitoring equipment can be found in many hospital settings. This allows a wide range of physiological parameters to be stored, which in turn allows clinicians and analysts to investigate a range of medical hypotheses. This paper introduces ACHE (architecture for clinical hypotheses examination), a framework specifically designed to support the preparation of such analyses. To evaluate the initial version of ACHE, a study to detect acute myocardial infarctions, was conducted with data from Glasgow Royal Infirmary´s Intensive Care Unit (ICU). Initial results from the study are very encouraging and ACHE substantially reduced the time required to perform the study. A study of the same phenomena across a much larger patient dataset will be undertaken shortly.