Title :
Integrated intravascular optical coherence tomography (OCT) - ultrasound (US) catheter for characterization of atherosclerotic plaques in vivo
Author :
JiaWen Li ; Xiang Li ; Jing, J. ; Mohar, D. ; Raney, A. ; Mahon, S. ; Brenner, Markus ; Qifa Zhou ; Patel, Pragati ; Shung, K. Kirk ; Zhongping Chen
Author_Institution :
Dept. of Biomed. Eng., Univ. of California, Irvine, Irvine, CA, USA
fDate :
Aug. 28 2012-Sept. 1 2012
Abstract :
A miniature integrated intravascular optical coherence tomography (OCT) - ultrasound (US) catheter for real-time imaging of atherosclerotic plaques has been developed, providing high resolution and deep tissue penetration at the same time. This catheter, with an outer diameter of 1.18mm, is suitable for imaging in human coronary arteries. The first in vivo 3D imaging of atherosclerotic microstructure in a rabbit abdominal aorta obtained by an integrated OCT-US catheter is presented. In addition, in vitro imaging of cadaver coronary arteries were conducted to demonstrate the imaging capabilities of this integrated catheter to classify different atherosclerotic plaque types.
Keywords :
biomedical ultrasonics; blood vessels; catheters; optical tomography; atherosclerotic microstructure; atherosclerotic plaque; deep tissue penetration; human coronary artery; integrated OCT-US catheter; integrated intravascular OCT; integrated intravascular optical coherence tomography; rabbit abdominal aorta; real time imaging; ultrasound catheter; Arteries; Atherosclerosis; Biomedical imaging; Catheters; Rabbits; Ultrasonic imaging; Animals; Aorta, Abdominal; Humans; Male; Plaque, Atherosclerotic; Rabbits; Tomography, Optical Coherence; Ultrasonography, Interventional;
Conference_Titel :
Engineering in Medicine and Biology Society (EMBC), 2012 Annual International Conference of the IEEE
Conference_Location :
San Diego, CA
Print_ISBN :
978-1-4244-4119-8
Electronic_ISBN :
1557-170X
DOI :
10.1109/EMBC.2012.6346639
