Integrated intravascular optical coherence tomography (OCT) - ultrasound (US) catheter for characterization of atherosclerotic plaques in vivo

Author

JiaWen Li ; Xiang Li ; Jing, J. ; Mohar, D. ; Raney, A. ; Mahon, S. ; Brenner, Markus ; Qifa Zhou ; Patel, Pragati ; Shung, K. Kirk ; Zhongping Chen

Author_Institution

Dept. of Biomed. Eng., Univ. of California, Irvine, Irvine, CA, USA

fYear

2012

fDate

Aug. 28 2012-Sept. 1 2012

Firstpage

3175

Lastpage

3178

Abstract

A miniature integrated intravascular optical coherence tomography (OCT) - ultrasound (US) catheter for real-time imaging of atherosclerotic plaques has been developed, providing high resolution and deep tissue penetration at the same time. This catheter, with an outer diameter of 1.18mm, is suitable for imaging in human coronary arteries. The first in vivo 3D imaging of atherosclerotic microstructure in a rabbit abdominal aorta obtained by an integrated OCT-US catheter is presented. In addition, in vitro imaging of cadaver coronary arteries were conducted to demonstrate the imaging capabilities of this integrated catheter to classify different atherosclerotic plaque types.

Keywords

biomedical ultrasonics; blood vessels; catheters; optical tomography; atherosclerotic microstructure; atherosclerotic plaque; deep tissue penetration; human coronary artery; integrated OCT-US catheter; integrated intravascular OCT; integrated intravascular optical coherence tomography; rabbit abdominal aorta; real time imaging; ultrasound catheter; Arteries; Atherosclerosis; Biomedical imaging; Catheters; Rabbits; Ultrasonic imaging; Animals; Aorta, Abdominal; Humans; Male; Plaque, Atherosclerotic; Rabbits; Tomography, Optical Coherence; Ultrasonography, Interventional;

fLanguage

English

Publisher

ieee

Conference_Titel

Engineering in Medicine and Biology Society (EMBC), 2012 Annual International Conference of the IEEE

Conference_Location

San Diego, CA

ISSN

1557-170X

Print_ISBN

978-1-4244-4119-8

Electronic_ISBN

1557-170X

Type

conf

DOI

10.1109/EMBC.2012.6346639

Filename

6346639