DocumentCode
2096106
Title
An analog circuit implementation of a Huber-Braun cold receptor neuron model
Author
Hermida, R. ; Patrone, M. ; Pijuan, M. ; Monzon, P. ; Oreggioni, Julian
Author_Institution
Fac. de Ingeniera, Univ. de la Republica, Montevideo, Uruguay
fYear
2012
fDate
Aug. 28 2012-Sept. 1 2012
Firstpage
3376
Lastpage
3379
Abstract
We present the design and implementation of an electronic device that, using off the shelf discrete analog components, implements the mathematical model of a cold receptor neuron called Huber-Braun. This model describes the electrical behavior of certain kinds of receptors when interacting with their environment, and it consists of a set of differential equations that has only been solved by numeric simulations. By these means a chaotic behavior has been found. An analog computer can be relevant for further analysis and validation of the model. The results obtained by means of numeric simulations and through our analog circuit simulator are consistent. In particular, temperature and external current bifurcation diagrams were successfully built. Finally, the electronic device allows the observation of all relevant variables and most of the expected behavior (tonic firing, chaotic, burst discharge, subthreshold oscillation and steady state).
Keywords
analogue circuits; analogue computers; bifurcation; biochemistry; bioelectric phenomena; biomembranes; cellular biophysics; chaos; differential equations; neural nets; numerical analysis; physiological models; Huber-Braun cold receptor neuron model; analog circuit implementation; analog circuit simulator; analog computer; chaotic behavior; differential equations; electrical behavior; electronic device; external current bifurcation diagrams; mathematical model; numeric simulation; shelf discrete analog components; temperature current bifurcation diagrams; Bifurcation; Biological system modeling; Integrated circuit modeling; Mathematical model; Neurons; Numerical models; Oscillators; Ion Channels; Membrane Potentials; Models, Neurological; Neurons; Nonlinear Dynamics;
fLanguage
English
Publisher
ieee
Conference_Titel
Engineering in Medicine and Biology Society (EMBC), 2012 Annual International Conference of the IEEE
Conference_Location
San Diego, CA
ISSN
1557-170X
Print_ISBN
978-1-4244-4119-8
Electronic_ISBN
1557-170X
Type
conf
DOI
10.1109/EMBC.2012.6346689
Filename
6346689
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