Validation of FFT-based algorithms for large-scale modeling of wave propagation in tissue

Investigates the accuracy of existing 2D pseudospectral and k-space formulations for acoustic propagation in tissue or model scattering media. They are intended to provide insight into tissue-ultrasound interaction and a “test bed” for aberration correction schemes in medical imaging. Both methods employ FFT´s to evaluate spatial derivatives to high accuracy on coarse grids. The primary difference lies in the approach to time integration. Scattering in large-scale, 2D, inhomogeneous media is included. The authors compare simulations against analytical solutions to illustrate spatial and temporal discretization required for acceptable solutions