A device for measurement of attenuation coefficient and phase velocity of nearly pure ultrasonic contrast agents

Author

Hughes, M.S. ; Marsh, J.N. ; Klibanov, A.L. ; Brandenburger, G.H. ; Miller, J.G.

Author_Institution

Mallinckrodt Inc., Hazelwood, MO, USA

Volume

2

fYear

1999

fDate

1999

Firstpage

1709

Abstract

Describes a technique for broadband measurements of the attenuation coefficient and phase velocity of highly attenuating liquid suspensions. To test the technique the authors apply it to the ultrasound contrast agent Albunex at concentrations ranging from 0.69×10⁶ particles/mL to 364×10⁶ particles/mL (0.1 to 50% concentration). These longitudinal wave measurements were performed on Albunex suspensions maintained at 37°C in a special time-domain reflectometer designed and constructed in the authors´ laboratory

Keywords

biomedical equipment; biomedical ultrasonics; suspensions; ultrasonic absorption; ultrasonic velocity measurement; 37 C; Albunex suspensions; highly attenuating liquid suspensions; longitudinal wave measurements; medical ultrasound imaging; nearly pure ultrasonic contrast agents; phase velocity; time-domain reflectometer; Acoustic pulses; Acoustic transducers; Attenuation measurement; Impedance; Laboratories; Phase measurement; Suspensions; Ultrasonic imaging; Ultrasonic variables measurement; Velocity measurement;

fLanguage

English

Publisher

ieee

Conference_Titel

Ultrasonics Symposium, 1999. Proceedings. 1999 IEEE

Conference_Location

Caesars Tahoe, NV

ISSN

1051-0117

Print_ISBN

0-7803-5722-1

Type

conf

DOI

10.1109/ULTSYM.1999.849327

Filename

849327