Title :
A CMOS chip for individual cell manipulation and detection
Author :
Manaresi, N. ; Romani, A. ; Medoro, G. ; Altomare, L. ; Leonardi, A. ; Tartagni, M. ; Guerrieri, R.
Author_Institution :
Silicon Biosystems, Bologna, Italy
Abstract :
Investigation of individual biological cell interactions on a large scale creates applications in drug screening, cell separation and cell analysis. The IC is designed to detect and manipulate more than 10k cells in parallel and includes a 320 /spl times/ 320 sensing and actuation array. The chip is implemented in 0.35/spl mu/m 2P 3M CMOS.
Keywords :
CMOS integrated circuits; application specific integrated circuits; biosensors; cellular biophysics; electric actuators; 0.35 micron; CMOS; actuation array; biological cell interactions; cell analysis; cell detection; cell manipulation; cell separation; drug screening; sensing array; Cells (biology); Circuits; Drugs; Electrodes; Fluid flow; Logic arrays; Optical sensors; Photodiodes; Sensor arrays; Voltage;
Conference_Titel :
Solid-State Circuits Conference, 2003. Digest of Technical Papers. ISSCC. 2003 IEEE International
Conference_Location :
San Francisco, CA, USA
Print_ISBN :
0-7803-7707-9
DOI :
10.1109/ISSCC.2003.1234262
