• DocumentCode
    2105826
  • Title

    A high density conduction based micro-DNA-identification array fabricated in a CMOS compatible process

  • Author

    Mei Xue ; Jiong Li ; Zuhong Lu ; Chuguang Feng ; Zhikuan Zhang ; Ko, P.K. ; Mansun Chan

  • Author_Institution
    Dept. of Electr. & Electron. Eng., Hong Kong Univ. of Sci. & Technol., China
  • fYear
    2003
  • fDate
    13-13 Feb. 2003
  • Firstpage
    198
  • Abstract
    A high-density CMOS-compatible DNA array fabricated using a modified metalization process is demonstrated. The array produces a conductivity difference of nine orders of magnitude for matched and single-based mismatched DNA molecules, which can be easily detected by a simple sensing circuit.
  • Keywords
    CMOS integrated circuits; DNA; biosensors; microsensors; CMOS compatible process; DNA molecules; conductivity difference; micro-DNA-identification array; modified metalization process; sensing circuit; single-based matched DNA; single-based mismatched DNA; Biomedical optical imaging; Bridge circuits; CMOS process; DNA; Fabrication; Gold; Metallization; Multiplexing; Probes; Self-assembly;
  • fLanguage
    English
  • Publisher
    ieee
  • Conference_Titel
    Solid-State Circuits Conference, 2003. Digest of Technical Papers. ISSCC. 2003 IEEE International
  • Conference_Location
    San Francisco, CA, USA
  • ISSN
    0193-6530
  • Print_ISBN
    0-7803-7707-9
  • Type

    conf

  • DOI
    10.1109/ISSCC.2003.1234265
  • Filename
    1234265