Title :
A CMOS-based on-chip neural interface device equipped with integrated LED array for optogenetics
Author :
Tokuda, Takashi ; Miyatani, T. ; Maezawa, Y. ; Kobayashi, Takehiko ; Noda, Toshio ; Sasagawa, Kiyotaka ; Ohta, Jun
Author_Institution :
Grad. Sch. of Mater. Sci., Nara Inst. of Sci. & Technol., Ikoma, Japan
fDate :
Aug. 28 2012-Sept. 1 2012
Abstract :
A novel CMOS-based neural interface device equipped with an integrated micro light source array was proposed and demonstrated. Target application of the device is optogenetics. GaInN LED array formed on sapphire substrate was successfully assembled with a multifunctional CMOS image sensor which is capable of injecting current via any of the pixel. We demonstrated addressable LED operation with the present device. The device has advantages such as simultaneous multi-site stimulation and on-chip optical imaging, that are not available with previously reported LED array device for optogenetics.
Keywords :
CMOS image sensors; bio-optics; biomedical optical imaging; gallium compounds; genetics; indium compounds; neural chips; GaInN; current injection; integrated LED array; micro light source array; multifunctional CMOS image sensor; on chip optical imaging; opCMOS based on chip neural interface device; optogenetics; simultaneous multisite stimulation; Arrays; CMOS image sensors; CMOS integrated circuits; Electrodes; Light emitting diodes; Optical imaging; System-on-a-chip; Equipment Design; Equipment Failure Analysis; Lighting; Neurons; Optogenetics; Photic Stimulation; Semiconductors; Signal Processing, Computer-Assisted; Systems Integration; Voltage-Sensitive Dye Imaging;
Conference_Titel :
Engineering in Medicine and Biology Society (EMBC), 2012 Annual International Conference of the IEEE
Conference_Location :
San Diego, CA
Print_ISBN :
978-1-4244-4119-8
Electronic_ISBN :
1557-170X
DOI :
10.1109/EMBC.2012.6347152
