DocumentCode
2109067
Title
Nonlinear mechanics of DNA doule strand: existence of the compact-envelope bright solitary wave
Author
Ndjoko, P.B. ; Bilbault, J. ; Binczak, S. ; Kofane, Temoleon Crepin
Author_Institution
LE2I Lab., Univ. of Burgundy, Dijon, France
fYear
2012
fDate
Aug. 28 2012-Sept. 1 2012
Firstpage
5428
Lastpage
5431
Abstract
We study the nonlinear dynamics of a homogeneous DNA chain which is based on site-dependent finite stacking and pairing enthalpies. We introduce an extended nonlinear Schrödinger equation describing the dynamics of modulated wave in DNA model. We obtain envelope bright solitary waves with compact support as a solution. Analytical criteria of existence of this solution are derived. The stability of bright compactons is confirmed by numerical simulations of the exact equations of the lattice. The impact of the finite stacking energy is investigated and we show that some of these compact bright solitary waves are robust, while others decompose very quickly depending on the finite stacking parameters.
Keywords
DNA; Schrodinger equation; functional analysis; molecular biophysics; molecular configurations; nonlinear dynamical systems; compact-envelope bright solitary wave; extended nonlinear Schrodinger equation; finite stacking energy; finite stacking enthalpy; homogeneous DNA chain; modulated wave; nonlinear dynamics; nonlinear mechanics; pairing enthalpy; DNA; Equations; Lattices; Mathematical model; Numerical stability; Stability analysis; Stacking; DNA; Models, Molecular; Nonlinear Dynamics; Nucleic Acid Conformation;
fLanguage
English
Publisher
ieee
Conference_Titel
Engineering in Medicine and Biology Society (EMBC), 2012 Annual International Conference of the IEEE
Conference_Location
San Diego, CA
ISSN
1557-170X
Print_ISBN
978-1-4244-4119-8
Electronic_ISBN
1557-170X
Type
conf
DOI
10.1109/EMBC.2012.6347222
Filename
6347222
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