• DocumentCode
    2109067
  • Title

    Nonlinear mechanics of DNA doule strand: existence of the compact-envelope bright solitary wave

  • Author

    Ndjoko, P.B. ; Bilbault, J. ; Binczak, S. ; Kofane, Temoleon Crepin

  • Author_Institution
    LE2I Lab., Univ. of Burgundy, Dijon, France
  • fYear
    2012
  • fDate
    Aug. 28 2012-Sept. 1 2012
  • Firstpage
    5428
  • Lastpage
    5431
  • Abstract
    We study the nonlinear dynamics of a homogeneous DNA chain which is based on site-dependent finite stacking and pairing enthalpies. We introduce an extended nonlinear Schrödinger equation describing the dynamics of modulated wave in DNA model. We obtain envelope bright solitary waves with compact support as a solution. Analytical criteria of existence of this solution are derived. The stability of bright compactons is confirmed by numerical simulations of the exact equations of the lattice. The impact of the finite stacking energy is investigated and we show that some of these compact bright solitary waves are robust, while others decompose very quickly depending on the finite stacking parameters.
  • Keywords
    DNA; Schrodinger equation; functional analysis; molecular biophysics; molecular configurations; nonlinear dynamical systems; compact-envelope bright solitary wave; extended nonlinear Schrodinger equation; finite stacking energy; finite stacking enthalpy; homogeneous DNA chain; modulated wave; nonlinear dynamics; nonlinear mechanics; pairing enthalpy; DNA; Equations; Lattices; Mathematical model; Numerical stability; Stability analysis; Stacking; DNA; Models, Molecular; Nonlinear Dynamics; Nucleic Acid Conformation;
  • fLanguage
    English
  • Publisher
    ieee
  • Conference_Titel
    Engineering in Medicine and Biology Society (EMBC), 2012 Annual International Conference of the IEEE
  • Conference_Location
    San Diego, CA
  • ISSN
    1557-170X
  • Print_ISBN
    978-1-4244-4119-8
  • Electronic_ISBN
    1557-170X
  • Type

    conf

  • DOI
    10.1109/EMBC.2012.6347222
  • Filename
    6347222