Title :
Nanotopography effects on astrocyte attachment to nanoporous gold surfaces
Author :
Kurtulus, O. ; Seker, E.
Author_Institution :
Dept. of Chem. Eng. & Mater. Sci., Univ. of California, Davis, Davis, CA, USA
fDate :
Aug. 28 2012-Sept. 1 2012
Abstract :
Nanoporous gold, synthesized by a self-assembly process, is a new biomaterial with desirable attributes, including tunable nanotopography, drug delivery potential, electrical conductivity, and compatibility with conventional microfabrication techniques. This study reports on the effect of nanotopography in guiding cellular attachment on nanoporous gold surfaces. While the changes in topography do not affect adherent cell density, average cell area displays a non-monotonic dependence on nanotopography.
Keywords :
biomedical materials; cellular biophysics; gold; nanomedicine; nanoporous materials; self-assembly; surface topography; Au; astrocyte attachment; biomaterial; cellular attachment guiding; compatibility; drug delivery potential; electrical conductivity; microfabrication; nanoporous gold surface; nanotopography effect; self assembly; tunable nanotopography; Adhesives; Computer architecture; Gold; Microprocessors; Nanotopography; Surface treatment; Animals; Astrocytes; Biocompatible Materials; Cell Adhesion; Cell Culture Techniques; Drug Delivery Systems; Electric Conductivity; Electrodes; Gold; Metal Nanoparticles; Mice; Microscopy, Electron, Scanning; Nanotechnology; Porosity; Temperature;
Conference_Titel :
Engineering in Medicine and Biology Society (EMBC), 2012 Annual International Conference of the IEEE
Conference_Location :
San Diego, CA
Print_ISBN :
978-1-4244-4119-8
Electronic_ISBN :
1557-170X
DOI :
10.1109/EMBC.2012.6347499
