Title :
Beamforming approach to phase-amplitude modulation analysis of multi-channel EEG
Author :
Sampson, A.L. ; Babadi, B. ; Prerau, M.J. ; Mukamel, E.A. ; Brown, Emery N. ; Purdon, P.L.
Author_Institution :
Dept. of Anesthesia, Massachusetts Gen. Hosp., Charlestown, MA, USA
fDate :
Aug. 28 2012-Sept. 1 2012
Abstract :
Phase-amplitude modulation is a form of cross frequency coupling where the phase of one frequency influences the amplitude of another higher frequency. It has been observed in neurophysiological recordings during sensory, motor, and cognitive tasks, as well as during general anesthesia. In this paper, we describe a novel beamforming procedure to improve estimation of phase-amplitude modulation. We apply this method to 64-channel EEG data recorded during propofol general anesthesia. The method improves the sensitivity of phase-amplitude analyses, and can be applied to a variety of multi-channel neuroscience data where phase-amplitude modulation is present.
Keywords :
amplitude modulation; array signal processing; electroencephalography; medical signal processing; neurophysiology; phase modulation; beamforming approach; cross frequency coupling; multichannel EEG; neurophysiological recordings; phase-amplitude modulation analysis; propofol general anesthesia; Anesthesia; Array signal processing; Brain models; Electroencephalography; Oscillators; Phase modulation; Algorithms; Anesthesia, General; Brain; Cognition; Electrodes; Electroencephalography; Fourier Analysis; Humans; Models, Statistical; Neurophysiology; Propofol; Regression Analysis; Signal Processing, Computer-Assisted; Software;
Conference_Titel :
Engineering in Medicine and Biology Society (EMBC), 2012 Annual International Conference of the IEEE
Conference_Location :
San Diego, CA
Print_ISBN :
978-1-4244-4119-8
Electronic_ISBN :
1557-170X
DOI :
10.1109/EMBC.2012.6347539
