Title :
Characterization of thin-film microelectrode array and signal conditioning microchip for high spatial resolution Surface Laplacian measurement
Author :
Huihang Dong ; Roussel, T. ; Jackson, D. ; Dosdal, Derek ; Ideker, Raymond
Author_Institution :
Depts. of Bioeng. & ECE, Univ. of Louisville, Louisville, KY, USA
Abstract :
Surface Laplacian (SL) electrograms have been found to be superior to unipolar electrograms in detecting local activation by providing local activation time, activation block and wavefront initiation information. Traditional electrode configurations do not provide adequate spatial resolution or signal-to-noise ratios (SNRs) to measure SLs accurately in vivo. The purpose of this work is to develop a customized thin-film microelectrode array (TFMEA) with a custom multichannel signal conditioning microchip (SCM) that significantly improves the SNRs to make high-quality SL measurements feasible. In vitro and in vivo testing and characterization results clearly demonstrate the ability of the TFMEA-SCM system to obtain detailed SL measurements.
Keywords :
biomedical measurement; medical signal processing; microelectrodes; microprocessor chips; signal conditioning circuits; TFMEA-SCM system; adequate spatial resolution; electrode configuration; high quality SL measurement; high spatial resolution surface Laplacian measurement; multichannel signal conditioning microchip; surface Laplacian electrogram; thin film microelectrode array; unipolar electrogram; wavefront initiation information;
Conference_Titel :
Sensors, 2010 IEEE
Conference_Location :
Kona, HI
Print_ISBN :
978-1-4244-8170-5
Electronic_ISBN :
1930-0395
DOI :
10.1109/ICSENS.2010.5690062