Title :
Identifying protein submitochondrial location by using features of sequence
Author :
FengMin Li ; Huanmin Zhou
Author_Institution :
Coll. of Sci., Inner Mongolia Agric. Univ., Hohhot, China
Abstract :
The function of proteins is closely related to it´s subcellular localization. With the number of sequences entering into databanks rapidly increasing, it is highly desirable to predict a protein subcellular localization from its amino acid sequence. In this paper, the amino acid composition, N-terminal region of protein sequence, the amino acid hydropathy composition and gene ontology are selected as feature parameters by using support vector machine. The predictive results show that our method is efficient to predict the protein submitochondrial localization.
Keywords :
bioinformatics; cellular biophysics; feature extraction; genetics; genomics; molecular biophysics; molecular configurations; ontologies (artificial intelligence); proteins; support vector machines; N-terminal region; amino acid hydropathy composition; amino acid sequence; databanks; feature parameter selection; features-of-sequence; gene ontology; protein function; protein subcellular localization; protein submitochondrial localization; support vector machine; amino acid; gene ontology; submitochondrial localization; support vector machine;
Conference_Titel :
Biomedical Engineering and Informatics (BMEI), 2012 5th International Conference on
Conference_Location :
Chongqing
Print_ISBN :
978-1-4673-1183-0
DOI :
10.1109/BMEI.2012.6513183