Title :
A novel L-Lactate sensor based on enzyme electrode modified with ZnO nanoparticles and multiwall carbon nanotubes
Author :
Wang, Y.T. ; Bao, Y.J. ; Lou, L. ; Li, J.J. ; Du, W.J. ; Zhu, Z.Q. ; Peng, H. ; Zhu, J.Z.
Author_Institution :
Institues for Adv. Interdiscipl. Res., East China Normal Univ., Shanghai, China
Abstract :
A highly sensitive and stable L-Lactate sensor based on the synergic action of multi-wall carbon nanotube (MWCNTs) and ZnO nanoparticles has been developed. The unique sandwich-like layer structure (PDDA/LOD/ZnO/MWCNTs) provides a favorable microenvironment to keep the bioactivity of LOD and prevent enzyme molecule leakage. Therefore, the proposed L-Lactate biosensor exhibited good analytical performances including high sensitivity and selectivity with satisfactory stability to amperometric determination of L-Lactate. The results indicated that the proposed PDDA/LOD/ZnO/MWCNTs film was an attractive matrix for the immobilization of LOD enzymes to fabricate biosensors.
Keywords :
biosensors; carbon nanotubes; electrochemical electrodes; electrochemical sensors; enzymes; sandwich structures; zinc compounds; C; L-lactate sensor; LOD enzyme immobilization; PDDA-LOD-ZnO-MWCNT film; ZnO; ZnO nanoparticle; lactate oxidase; multiwall carbon nanotube; nanomaterial modified enzyme electrode; polydiallyldimethylammonium chloride; sandwich like layer structure;
Conference_Titel :
Sensors, 2010 IEEE
Conference_Location :
Kona, HI
Print_ISBN :
978-1-4244-8170-5
Electronic_ISBN :
1930-0395
DOI :
10.1109/ICSENS.2010.5690980
