A Method for Solving Overlap Problem in Spike Sorting Based on Genetic Algorithm

Overlap decomposition is one of the difficulties in spike sorting. A method based on genetic algorithm is proposed to deal with the overlapped signal from two single waves in this paper. Specifically, with the reliable signal wave templates given, the methods for overlap signals and for single wave signals are used simultaneously to process the unknown data from the signal acquisition equipment, and then the best is selected as the final solution. The method for overlap signals is of genetic algorithm, while the one for single wave signals is of template matching. Genetic algorithm, or even intelligence algorithm is seldom adopted by the past work of dealing with overlapped signals in spike sorting and the simulation experiments indicate that the method put forward in this paper possesses satisfying accuracy and robustness.