DocumentCode :
2154538
Title :
Simultaneous Dual-Isotope SPECT Imaging Using Independent Component Analysis Based on Wavelet Transformation: Wavelet Based Dual-Isotope SPECT Imaging Using ICA Analysis
Author :
Yang, Bang-Hung ; Wang, Shyh-Jen ; Chou, Yuan-Hwa ; Chen, Jyh-Cheng
Author_Institution :
Dept. of Biomed. Imaging & Radiol. Sci., Nat. Yang-Ming Univ., Taipei, Taiwan
fYear :
2009
fDate :
17-19 Oct. 2009
Firstpage :
1
Lastpage :
3
Abstract :
Simultaneous dual-isotope imaging from two different energy gamma rays such as Tc-99m (140 keV) and I-123 (159 keV) is an unusual yet useful technology. Its advantages are less acquisition time, the same physiological condition, and better spatial registration. However, the disadvantages of dual-isotope technique are the scatter and cross-talk effect because of overlapping between two nearby photopeaks. We proposed a new method to correct cross-talk from primary and scattered photons through wavelet transformation followed by independent component analysis with multiple energy windows (W_eICA). We simulated dual-isotope digital images with five, six, and seven energy windows using SimSET software to generate scattered noise. We compared those images between W_eICA and standalone eICA method. According to our results, we verified the performance of WeICA in separating Tc-99m and I-123 energy spectra generated from the SimSET Monte Carlo simulation. W_eICA method not only decreased the number of energy windows required but also separated dual-isotope photopeaks correctly. The results have demonstrated that the W_eICA method improved the quantitative accuracy and might be an effective tool for simultaneous dual-isotope SPECT imaging.
Keywords :
Monte Carlo methods; deconvolution; independent component analysis; medical signal processing; single photon emission computed tomography; wavelet transforms; I-123 energy spectra; SimSET Monte Carlo simulation; Tc-99m energy spectra; W_eICA; cross talk correction; cross talk effects; electron volt energy 140 keV; electron volt energy 159 keV; gamma-rays; independent component analysis; multiple energy window; scatter effects; wavelet based dual isotope SPECT imaging; wavelet transformation; Crosstalk; Digital images; Electromagnetic scattering; Gamma rays; Image analysis; Independent component analysis; Optical imaging; Particle scattering; Single photon emission computed tomography; Wavelet analysis;
fLanguage :
English
Publisher :
ieee
Conference_Titel :
Image and Signal Processing, 2009. CISP '09. 2nd International Congress on
Conference_Location :
Tianjin
Print_ISBN :
978-1-4244-4129-7
Electronic_ISBN :
978-1-4244-4131-0
Type :
conf
DOI :
10.1109/CISP.2009.5304064
Filename :
5304064
Link To Document :
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