Title :
SeizAlert: Seizure forewarning via scalp EEG
Author :
Hively, Lee M. ; Munro, Nancy B.
Author_Institution :
Oak Ridge Nat. Lab., Oak Ridge, TN
Abstract :
SeizAlert is a low-cost, wearable device to forewarn of an impending epileptic seizure. The technology, covered by eight patents, presently uses brain-wave data from four scalp electrodes at the front of the scalp, removes eye-blink (and other muscular) artifacts that would otherwise confound the analysis, converts the artifact-filtered data into a statistical distribution function (DF), and compares the DF for the baseline period with subsequent DFs via statistical measures of dissimilarity. Several hours forewarning of an impending event is provided by multiple, successive occurrences of the dissimilarity measures above a threshold. The resultant total true rate is 93% with a false positive rate that is more than an order of magnitude below the clinically acceptable value. R&D Magazine awarded its prestigious R&D 100 Award to SeizAlert in 2005.
Keywords :
biomedical electrodes; diseases; electroencephalography; neurophysiology; seizure; statistical distributions; EEG; SeizAlert technology; artifact-filtered data; brain-wave data; dissimilarity measurement; epileptic seizure; impending event; low-cost device; scalp electrode; statistical distribution function; Biomedical measurements; Biomedical monitoring; Contracts; Drugs; Electroencephalography; Epilepsy; Medical diagnostic imaging; Medical treatment; Nonlinear filters; Scalp;
Conference_Titel :
Biomedical Science & Engineering Conference, 2009. BSEC 2009. First Annual ORNL
Conference_Location :
Oak Ridge, TN
Print_ISBN :
978-1-4244-3837-2
DOI :
10.1109/BSEC.2009.5090475