Title :
Spatio-temporal self-calibration of optical dynamical biochip
Author :
Hottin, Jéme ; Lecaruyer, Pierre ; Spadavecchia, Jolanda ; Roger, Giséle ; Moreau, Julien ; Canva, Michael
Author_Institution :
Univ Paris Sud, Palaiseau
Abstract :
The authors propose a self-calibration approach to compensate the response dispersion on biochips due to the non homogeneous surface layers. Such effect of probe concentration has been quantified in the case of a DNA biochip.
Keywords :
DNA; biosensors; calibration; optical sensors; spatiotemporal phenomena; DNA biochip; biosensor; nonhomogeneous surface layers; optical dynamical biochip; optical sensor; probe concentration; response dispersion; spatio-temporal self-calibration; Biomedical optical imaging; DNA; Kinetic theory; Monitoring; Optical buffering; Optical imaging; Optical refraction; Plasmons; Probes; Resonance; interaction kinetic monitoring; optical biosensor; self-calibration; surface functionalization; surface plasmon resonance imaging;
Conference_Titel :
Lasers and Electro-Optics, 2007 and the International Quantum Electronics Conference. CLEOE-IQEC 2007. European Conference on
Conference_Location :
Munich
Print_ISBN :
978-1-4244-0931-0
Electronic_ISBN :
978-1-4244-0931-0
DOI :
10.1109/CLEOE-IQEC.2007.4386641