DocumentCode
2167640
Title
Assessing the binding mode of ligands to DNA by time resolved fluorescence
Author
Nardo, L. ; Bondani, M. ; Andreoni, A.
Author_Institution
Insubria Univ., Como
fYear
2007
fDate
17-22 June 2007
Firstpage
1
Lastpage
1
Abstract
Being able to determine the binding mode of a ligand to DNA, typically base intercalation (BI) or minor groove binding (MGB), is critical to determine the ligand therapeutic effects. Still, drug designers can only gain such information by means of indirect, complicated and very expensive methods.
Keywords
DNA; binding energy; fluorescence; time resolved spectroscopy; DNA; base intercalation; ligand binding mode; ligand therapeutic effects; minor groove binding; time resolved fluorescence; Bismuth; Bonding; DNA; Drugs; Fluorescence; Laboratories; Laser excitation; Laser stability; Sequences; Ultrafast optics;
fLanguage
English
Publisher
ieee
Conference_Titel
Lasers and Electro-Optics, 2007 and the International Quantum Electronics Conference. CLEOE-IQEC 2007. European Conference on
Conference_Location
Munich
Print_ISBN
978-1-4244-0931-0
Electronic_ISBN
978-1-4244-0931-0
Type
conf
DOI
10.1109/CLEOE-IQEC.2007.4386659
Filename
4386659
Link To Document