Title :
Phantom studies investigating extravascular density imaging for partial volume correction of 3D PET 18FDG studies
Author :
Wassenaar, Richard W. ; Beanlands, Rob S B ; DeKemp, Robert A.
Author_Institution :
Carleton Univ., Ottawa, Ont., Canada
Abstract :
Limited scanner resolution and cardiac motion contribute to partial volume (PV) averaging of cardiac PET images. An extravascular (EV) density image, created from the subtraction of a blood pool scan from a transmission image, has been used to correct for PV averaging in H215O studies using 2D imaging but not with 3D imaging of other tracers such as 18FDG. A cardiac phantom emulating the left ventricle was used to characterize the method for use in 3D PET studies. Measurement of the average myocardial activity showed PV losses of 32% below the true activity (p<0.001).
Keywords :
cardiology; positron emission tomography; 2D imaging; 3D PET 18FDG studies; average myocardial activity; cardiac motion; cardiac phantom; extravascular density imaging; left ventricle; limited scanner resolution; partial volume correction; Blood; Data acquisition; Heart; Image resolution; Imaging phantoms; Loss measurement; Myocardium; Plastics; Positron emission tomography; Spatial resolution;
Conference_Titel :
Nuclear Science Symposium Conference Record, 2002 IEEE
Print_ISBN :
0-7803-7636-6
DOI :
10.1109/NSSMIC.2002.1239451