Title : 
Phantom studies investigating extravascular density imaging for partial volume correction of 3D PET 18FDG studies
         
        
            Author : 
Wassenaar, Richard W. ; Beanlands, Rob S B ; DeKemp, Robert A.
         
        
            Author_Institution : 
Carleton Univ., Ottawa, Ont., Canada
         
        
        
        
        
        
            Abstract : 
Limited scanner resolution and cardiac motion contribute to partial volume (PV) averaging of cardiac PET images. An extravascular (EV) density image, created from the subtraction of a blood pool scan from a transmission image, has been used to correct for PV averaging in H215O studies using 2D imaging but not with 3D imaging of other tracers such as 18FDG. A cardiac phantom emulating the left ventricle was used to characterize the method for use in 3D PET studies. Measurement of the average myocardial activity showed PV losses of 32% below the true activity (p<0.001).
         
        
            Keywords : 
cardiology; positron emission tomography; 2D imaging; 3D PET 18FDG studies; average myocardial activity; cardiac motion; cardiac phantom; extravascular density imaging; left ventricle; limited scanner resolution; partial volume correction; Blood; Data acquisition; Heart; Image resolution; Imaging phantoms; Loss measurement; Myocardium; Plastics; Positron emission tomography; Spatial resolution;
         
        
        
        
            Conference_Titel : 
Nuclear Science Symposium Conference Record, 2002 IEEE
         
        
            Print_ISBN : 
0-7803-7636-6
         
        
        
            DOI : 
10.1109/NSSMIC.2002.1239451