Age dependency of cortex values before and after partial volume correction in PET data

Author

Kops, Elena Rota ; Storb, Sebastian H. ; Herzog, Hans R. ; Bauer, Andreas

Author_Institution

Inst. of Medicine, Res. Center Julich GmbH, Germany

Volume

2

fYear

2002

fDate

10-16 Nov. 2002

Firstpage

850

Abstract

The age dependency observed in many PET brain studies may be caused by pathophysiological and/or instrumental reasons. There is a decisive influence of the partial volume (PV) effect and its correction in studies comparing young and elderly subjects when regional cerebral atrophy is involved. A combined group of healthy volunteers (n=12; 21-74 yr.) and patients with Parkinson´s disease (PD) (n=12; 42-75 yr.) were scanned with MR and PET. Firstly, the MR data were segmented into gray matter (GM), white matter (WM), as well as cerebral spinal fluid (CSF). After creating simulated images from these data by setting fixed values to the three tissue types, these images were filtered with the image PET resolution.

Keywords

biomedical MRI; brain; diseases; image segmentation; medical image processing; positron emission tomography; 21 to 74 year; 42 to 75 year; MR imaging; PET; Parkinson´s disease; age dependency; brain studies; cerebral spinal fluid; cortex values; gray matter; image segmentation; partial volume; partial volume correction; positron emission tomography; regional cerebral atrophy; white matter; Atrophy; Attenuation; Biomedical imaging; Image resolution; Image segmentation; Instruments; Magnetic separation; Parkinson´s disease; Positron emission tomography; Senior citizens;

fLanguage

English

Publisher

ieee

Conference_Titel

Nuclear Science Symposium Conference Record, 2002 IEEE

Print_ISBN

0-7803-7636-6

Type

conf

DOI

10.1109/NSSMIC.2002.1239458

Filename

1239458