Title :
Open Transverse ElectroMagnetic (TEM) cell as applicator of high-intensity nsPEFs and electro-optic measurements
Author :
Kohler, Sophie ; Thi Dan Thao Vu ; Vernier, P.T. ; Arnaud-Cormos, D. ; Leveque, P.
Author_Institution :
XLIM Res. Inst., Univ. of Limoges, Limoges, France
Abstract :
To expose biological cells or tissues to nanosecond pulsed electric fields of high intensity (>>kV/cm) and subnanosecond rise time, broadband exposure system with high-voltage handling capabilities and compatible with the tools of biologists are needed. To deliver subnanosecond pulses to a biological target, a hyperband antenna has been reported. In this study, we propose to use a Transverse ElectroMagnetic (TEM) cell. We characterize the system experimentally and numerically with Gaussian-like pulses of about 1.2 ns and 1.8 kV amplitude. The results are compared with those obtained using a classical electroporation cuvette, a typical delivery system to expose cell suspensions to ultrashort pulsed electric fields.
Keywords :
TEM cells; biological tissues; biomedical equipment; biomedical measurement; cellular biophysics; electro-optical effects; numerical analysis; patient treatment; pulsed power technology; suspensions; Gaussian-like pulses; TEM cell; biological cells; biological tissues; broadband exposure system; cell suspensions; classical electroporation cuvette; electro-optic measurements; high-intensity nsPEF; high-voltage handling capabilities; hyperband antenna; nanosecond pulsed electric fields; transverse electromagnetic cell; ultrashort pulsed electric fields; Finite-Difference Time-Domain (FDTD); Nanosecond Pulsed Electric Field (nsPEF); Transverse ElectroMagnetic cell; high-intensity;
Conference_Titel :
Power Modulator and High Voltage Conference (IPMHVC), 2012 IEEE International
Conference_Location :
San Diego, CA
Print_ISBN :
978-1-4673-1222-6
DOI :
10.1109/IPMHVC.2012.6518857
