Title :
Electroporation mechanism: Review of molecular models based on computer simulation
Author :
Apollonio, F. ; Liberti, M. ; Marracino, P. ; Mir, Lluis
Author_Institution :
Dept. of Inf. Eng., Electron. & Telecommun., Sapienza Univ. of Rome, Rome, Italy
Abstract :
A review of molecular models explaining the basic mechanism of electroporation is presented. Essentially it is argued that the electric field applied is able to promote pore formation on the lipid bilayer, but different parameters may play a key role.
Keywords :
bioelectric phenomena; biology computing; electric fields; molecular biophysics; computer simulation; electric field; electroporation mechanism; lipid bilayer; molecular models; pore formation; Biological system modeling; Biomembranes; Computational modeling; Computer simulation; Electric fields; Lipidomics; Physiology; atomistic modeling; electric field; electroporation; membrane bilayer; molecular dynamics;
Conference_Titel :
Antennas and Propagation (EUCAP), 2012 6th European Conference on
Conference_Location :
Prague
Print_ISBN :
978-1-4577-0918-0
Electronic_ISBN :
978-1-4577-0919-7
DOI :
10.1109/EuCAP.2012.6206719
