Sulcal variability in a computerized brain atlas

Computerized sulci atlas includes a mean representation of a standard brain in a standardized coordinate space, such as the Talairach´s grid. In this reference system, differences between sulci at the surface of the brain are due to shape differences of the brain and to intrinsic anatomical differences of sulci. In this paper, four different methods are compared: non-proportional, global linear, local linear (Talairach) and nonlinear methods. From nine brains where sulci are labeled, a model of their mean location and its variability is computed. As expected, the nonlinear method is the most accurate one, with fewer variations than others