Title :
Mechanics of aortic valve leaflet mesostructures
Author :
Rock, C.A. ; Doehring, T.
Author_Institution :
Sch. of Biomed. Eng., Sci. & Health Syst., Drexel Univ., Philadelphia, PA, USA
Abstract :
Current bioprosthetic and mechanical designs or heart valve replacements do not fully consider the underlying native fibre structure of the valve, nor their fibre-scale properties. The overall goal of this work is to perform experimental and analytical analyses of the individual fiber and membrane “Mesostructures” of the aortic heart valve. We have developed a novel experimental/analytical system to investigate the properties of these structures in detail. More successful treatments of damaged or diseased valves require new experiments and mathematical models at the tissue level by which to evaluate and improve valve repair/replacement designs.
Keywords :
biological tissues; biomechanics; biomembranes; cardiology; cellular biophysics; diseases; fibres; physiological models; prosthetics; aortic heart valve replacement; aortic valve leaflet mesostructures; bioprosthetic; fibre-scale properties; mathematical models; mechanical designs; membrane mesostructures; native fibre structure; tissue level; valve repair-replacement designs; Biomechanics; Biomembranes; Heart; Optical fibers; Strain; Testing; Valves; aortic valve; biomechanics; heart valve; mesostructures; soft tissue testing;
Conference_Titel :
Bioengineering Conference (NEBEC), 2012 38th Annual Northeast
Conference_Location :
Philadelphia, PA
Print_ISBN :
978-1-4673-1141-0
DOI :
10.1109/NEBC.2012.6206961