Title :
Hot-Embossed Piezoelectric Polymer Micro-Diaphragm Arrays Integrated with Lab-on-a-Chip for Protein Analysis
Author :
Li, Chunyan ; Wu, Pei-Ming ; Browne, Andrew ; Lee, Soohyun ; Ahn, Chong H.
Author_Institution :
Univ. of Cincinnati, Cincinnati
Abstract :
Piezoelectric copolymer, PVDF-TrFE, diaphragm arrays with integrated microfluidic chip for high performance protein immunosensors were developed and characterized in this work. Mold-transfer and hot-embossing techniques provide a high throughput and repeatable way to fabricate piezoelectric polymer diaphragms and PVDF-TrFE´s hydrophobic surface acts as a natural bioreceptor to capture proteins of interest. In addition, integrated microfluidic devices enhance reaction efficiency and reduce the assay time.
Keywords :
biosensors; embossing; lab-on-a-chip; microfluidics; moulding; piezoelectric devices; polymer blends; proteins; high performance protein immunosensors; hot-embossing techniques; hydrophobic surface; integrated microfluidic chip; integrated microfluidic device; lab-on-a-chip; mold-transfer technique; natural bioreceptor; piezoelectric copolymer; piezoelectric polymer diaphragms; piezoelectric polymer micro-diaphragm arrays; protein analysis; Fabrication; Immune system; Immunity testing; Lab-on-a-chip; Microchannel; Microfluidics; Polymers; Proteins; Resonant frequency; Substrates;
Conference_Titel :
Sensors, 2007 IEEE
Conference_Location :
Atlanta, GA
Print_ISBN :
978-1-4244-1261-7
Electronic_ISBN :
1930-0395
DOI :
10.1109/ICSENS.2007.4388436
