Assemble single stranded DNA and gold nanoparticle complexes onto the surface of RBC

This work aims to assemble single stranded DNA(ssDNA) and gold nanoparticles(AuNPs) into microstructures. The building units of the microstructure first consist of two AuNPs each with one of two sequences of ssDNA attached to their surfaces each with a fluorophore at the free end. A larger piece of hairpin loop ssDNA will then be added with each of its ends complimentary to one of the two ssDNA strands already on the AuNPs. A red blood cell is used as a template for DNA and gold nanoparticles to assemble around. ssDNA-AuNPs binding was confirmed using confocal laser scanning microscope which shows fluorescence in samples after binding.