DocumentCode
2208890
Title
A Ferrofluid Immunoassay Based on Magnetic Field-Induced Birefringence
Author
Ku, Ben Y. ; Horsley, David A.
Author_Institution
Univ. of California, Davis
fYear
2007
fDate
28-31 Oct. 2007
Firstpage
1089
Lastpage
1092
Abstract
An immunoassay is described based on optical detection of the frequency-dependent magnetic relaxation signal in a ferrofluid. The binding of antibodies to magnetic nanoparticles in the ferrofluid causes changes in the magnetic relaxation signal due to an increase in the nanoparticle diameter. The addition of 16.1 ng of antibodies to a 100 mul ferrofluid sample results in an increase in average nanoparticle diameter from 109 nm to 250 mn.
Keywords
biomedical measurement; biosensors; birefringence; magnetic fields; magnetic fluids; magnetic relaxation; nanobiotechnology; nanoparticles; ferrofluid immunoassay; frequency-dependent magnetic relaxation signal; magnetic field-induced birefringence; magnetic nanoparticles; nanoparticle diameter; optical detection; Birefringence; Immune system; Magnetic field measurement; Magnetic fields; Magnetic materials; Magnetic separation; Nanoparticles; Optical refraction; Optical sensors; Optical variables control;
fLanguage
English
Publisher
ieee
Conference_Titel
Sensors, 2007 IEEE
Conference_Location
Atlanta, GA
ISSN
1930-0395
Print_ISBN
978-1-4244-1261-7
Electronic_ISBN
1930-0395
Type
conf
DOI
10.1109/ICSENS.2007.4388595
Filename
4388595
Link To Document