Instrumentation of the awake unrestrained rat for ECG and respiration

Author

Soldan, S.A. ; Reisman, S. ; Bergen, M.T. ; Servatius, R.J.

Author_Institution

New Jersey Inst. of Technol., Newark, NJ, USA

fYear

1997

fDate

21-22 May 1997

Firstpage

29

Lastpage

30

Abstract

Our goal was to record electrocardiogram (ECG) and respiration data from an awake, freely moving rat. The technique presented here requires simple surgery in which two electrodes and a ground wire are placed subcutaneously across the chest, which is externalized via a connector on the top of the subjects head. From these leads it is possible to collect ECG in a standard two lead configuration, and respiration with impedance pneumography. Utilizing electrode placement and signal filtering we were able to obtain ECG from anaesthetized, and awake rats without the effects of motion artifact. Respiration was collected with little effect of motion in all but one subject which displayed excessive movement

Keywords

biological techniques; biology computing; electric impedance measurement; electrocardiography; flow measurement; medical signal processing; pneumodynamics; surgery; ECG data; awake freely moving rat; awake unrestrained rat; chest; connector; electrocardiogram; electrode placement; electrodes; ground wire; head; impedance pneumography; instrumentation; motion artifact; respiration data; signal filtering; simple surgery; standard two lead configuration; Connectors; Electrocardiography; Electrodes; Filtering; Impedance; Instruments; Magnetic heads; Rats; Surgery; Wire;

fLanguage

English

Publisher

ieee

Conference_Titel

Bioengineering Conference, 1997., Proceedings of the IEEE 1997 23rd Northeast

Conference_Location

Durham, NH

Print_ISBN

0-7803-3848-0

Type

conf

DOI

10.1109/NEBC.1997.594942

Filename

594942