Research of Morphology Quantification Algorithm on DNA Polymorphism Individual Identifying

Polymorphism individual identifying of DNA was the image pattern-recognition of the oligonucleotide chip scan photo. The authors of this paper propose their own functions which aim at the issue of bit dot computer recognition of oligonucleotide chip scan photo: implemented chip-scan photo binarization after the determination of threshold-value by using OSTU. Sub-image segmentation and separately processing were adopted to achieve mathematical morphology and quantification in chip-scan photo information processing; find the image edge line of the sample spot by tracking function, then obtain the sample dots´ area by using approximation curve algorithm and integral, and compare with the standard sample dots to get its binary value. The paper also introduced the information collection algorithm design process.